UFC 321 is set for October 25 at Abu Dhabi’s Etihad Arena, featuring two high-profile title fights. In the main event, Tom Aspinall will defend his heavyweight belt against former interim champion Ciryl Gane. Meanwhile, Mackenzie Dern faces Virna Jandiroba for the vacant women’s strawweight championship in the co-main event. Odds currently favour Aspinall and Dern, but both fights are expected to deliver drama and showcase top-level MMA skill.
Introduction to UFC 321
UFC 321 brings two major title fights to Abu Dhabi’s Etihad Arena on October 25, 2025, making it one of the most anticipated events of the year. Reigning heavyweight champion Tom Aspinall will defend his title against former interim champion Ciryl Gane in the main event. In the co-main, Mackenzie Dern and Virna Jandiroba will battle for the vacant women’s strawweight belt.
Both fights carry significant stakes, with fighters aiming to cement their legacies. UFC 321 promises an action-packed night, combining championship-level striking, grappling, and strategy. Fans and bettors alike are eagerly analysing odds, fight styles, and potential outcomes as the event draws near.
Tom Aspinall vs. Ciryl Gane Odds
Tom Aspinall enters the main event as a heavy favourite at -400, while Ciryl Gane is the underdog at +300. Aspinall has a reputation as a knockout artist, with 12 of his 15 wins coming via KO. His striking and Brazilian jiu-jitsu black belt make him a formidable opponent for Gane, who will rely on his movement and experience as a former interim champion.
Fans can expect a tactical matchup where Aspinall looks to impose his power while Gane uses footwork and agility to avoid heavy shots. The contrast in styles sets the stage for an intriguing heavyweight clash.
Mackenzie Dern vs. Virna Jandiroba Odds
In the co-main event, Mackenzie Dern is slightly favoured at -175, while Virna Jandiroba sits at +150. Dern brings an improved striking game alongside her renowned submission skills, with eight career wins via submission. Jandiroba is a grappling specialist, averaging 4.57 takedowns per 15 minutes with a 50% success rate, which could be pivotal in controlling the fight.
This matchup highlights a classic striker-versus-grappler scenario. Dern’s challenge will be to keep the fight standing and capitalize on her striking improvements, while Jandiroba aims to bring the fight to the ground and dictate the pace.
Fight Analysis
In the heavyweight clash, Aspinall’s knockout power and grappling acumen may prove decisive against Gane, who relies on speed and movement. Aspinall will need to manage Gane’s evasiveness while finding openings to secure significant strikes or submissions.
For the co-main, Dern and Jandiroba’s contrasting skill sets create a dynamic fight. Dern’s striking and submission versatility will be tested against Jandiroba’s relentless grappling. The winner will likely be the fighter who can implement their strategy most effectively under pressure.
Expert Picks and Predictions
Experts expect Tom Aspinall to win by TKO, likely in rounds two or three, given his striking power and ability to adapt. Mackenzie Dern is predicted to win by decision, relying on her striking improvements and overall ground game against Jandiroba’s grappling dominance.
Both fights carry high stakes, with title implications and division rankings on the line. Fans should watch closely for strategic exchanges and momentum shifts that could determine the outcome.
Additional Matchups
UFC 321 also features five additional bouts, adding depth to an already stacked card. Notable fights include Umar Nurmagomedov facing Mario Bautista, Alexander Volkov vs. Jailton Almeida, and Azamat Murzakanov taking on Aleksandar Rakić. Each matchup brings unique storylines, showcasing emerging contenders and established fighters aiming to make an impact.
Conclusion
UFC 321 promises an unforgettable night of high-level MMA action. With Tom Aspinall defending the heavyweight title against Ciryl Gane and Mackenzie Dern vying for the strawweight championship against Virna Jandiroba, fans can expect skill, strategy, and championship stakes.
The undercard also adds intrigue, offering additional fights that could shake up the rankings. UFC 321 in Abu Dhabi is shaping up to be a must-watch event for MMA enthusiasts and bettors alike.
Frequently Asked Questions
What is significant about UFC 321 for Tom Aspinall?
It marks his first title defense as the heavyweight champion following his rise after Jon Jones’s retirement.
How does Mackenzie Dern’s style help her against Virna Jandiroba?
Dern combines improved striking with submission expertise, making her adaptable whether the fight stays standing or goes to the ground.
What are the betting odds for the main fights?
Aspinall is -400 vs. Gane at +300, while Dern is -175 vs. Jandiroba at +150.
What do experts predict for the title fights?
Aspinall is expected to win by TKO in rounds two or three, and Dern is projected to win by decision.
What else can fans expect from UFC 321?
Five additional matchups across weight classes, featuring both title fights and emerging contenders.
